Data collection and analysis:. Ten studies were rated at high risk of bias. Common side effects associated with 5-ASA included flatulence, abdominal pain, nausea, diarrhea, headache, dyspepsia indigestionand nasopharyngitis inflammation of the nasal passages. No statistically significant differences in efficacy or adherence were found between once daily and conventionally dosed 5-ASA. Up to a third of patients treated with SASP have reported side effects, which are thought to be related to the sulfur part of the molecule. Common side effects associated with SASP include nausea, indigestion, headache, vomiting and abdominal pain. Placebo-controlled trials were subgrouped by dosage. Oral vitamin B12 compared with intramuscular vitamin B12 for vitamin B12 deficiency Review question Does oral vitamin B 12 have similar effects as intramuscular injections of vitamin B 12 for people with vitamin B 12 deficiency? High dose therapy appears to be as safe as low dose and is not associated with a higher incidence of adverse events.
L Zhang, S Jia, Y Ma, L Li, X Li, X Wang, X Fu, W Ma, Y Qin, W Li, J Wu, Z Sun, X Zhang, F Nan, Y Chang, Z Li, D Zhang, G Wang, J Yan, L Su, J Wang, H Xue. Authors: Wang Y, Parker CE, Feagan BG, MacDonald JK. Primary Review Group: IBD Group · See the full Review on. the Cochrane Library.
▻. Wang H, Li L, Qin L, Song Y, Vidal-Alaball J, Liu T.
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Primary Review Group: Metabolic and Endocrine Disorders Group · See the full Review on.
Main results:. Ten studies were rated at high risk of bias.
We found very low-quality evidence that oral vitamin B 12 appears as safe as IM vitamin B Further trials should conduct better randomisation and blinding procedures, recruit more participants, and provide adequate reporting. Studies were accepted for analysis if they were randomized controlled trials with a minimum treatment duration of six months.
Kuang P, Dong T, Wang L, Wei X, Liu T. Tacrolimus versus cyclosporine A for. Cochrane Response, operated by The Cochrane Collaboration.
Registered Mortality after RV1 introduction () in children <1 year compared Mast T. C, Wang F. T, Su S, Seeger J. D. Evidence of herd immunity and sustained.
Three RCTs met our inclusion criteria. Background Vitamin B 12 cobalamin is necessary for basic body functions, such as the growth and development of red blood cells and the nervous system.
One trial stated that no treatment-related adverse events were seen in both the oral and IM vitamin B 12 groups. There was a trend towards greater efficacy with higher doses of 5-ASA with a statistically significant benefit for the 1 to 1. The studies randomised participants 74 participants to oral vitamin B 12 and 79 participants to intramuscular vitamin B This updated review includes more recent studies and evaluates the effectivenessdose-responsiveness, and safety of 5-ASA preparations used for maintenance of remission in quiescent ulcerative colitis.
Endocrine regulation of cervical ripening in. In addition, we outline the latest of the latest Cochrane Reviews (10–15) the EORTC trial) will lead to a more definitive answer with respect to OS. . Wang.
L. Wei. X. Liu. T. Tacrolimus versus cyclosporine A for. Editor: Tom Jefferson, Cochrane Acute Respiratory Infections Group, Italy. Received December 15 . All ages and at-risk groups no no. Wang. . Cochrane. S. R. Jan. O/Z/L.
Oral 5ASA compounds for maintaining remission in ulcerative colitis Cochrane
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We used standard methodological procedures expected by Cochrane. Common side effects associated with SASP include nausea, indigestion, headache, vomiting and abdominal pain. One study stated that no treatment-related side effects were seen in both the oral and intramuscular vitamin B 12 groups. This may have reduced SASP-related side effects in these trials.
One trial stated that no treatment-related adverse events were seen in both the oral and IM vitamin B 12 groups. We found three randomised controlled studies clinical studies where people are randomly put into one of two or more treatment groups. This updated review includes more recent studies and evaluates the effectivenessdose-responsiveness, and safety of 5-ASA preparations used for maintenance of remission in quiescent ulcerative colitis.
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|Oral 5-ASA administered once daily is as effective and safe as conventional dosing two or three times daily for maintaining remission in ulcerative colitis. Health topics:. One trial stated that no treatment-related adverse events were seen in both the oral and IM vitamin B 12 groups.
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Secondary outcomes were health-related quality of life, acceptability to patients, haemoglobin and mean corpuscular volume, total homocysteine and serum methylmalonic acid levels, and socioeconomic effects. Oral 5-ASA administered once daily is as effective and safe as conventional dosing for maintenance of remission in quiescent ulcerative colitis.
Quality of the evidence The overall quality of the evidence was low or very low, mainly due to the small number of included studies and the low numbers of participants in these studies. The overall quality of evidence for this outcome was low due to serious imprecision low number of trials and participants.